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| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Please contact Customer Service for Availability | 2 710,00 CZK |
50 mg | Please contact Customer Service for Availability | 10 900,00 CZK 9 265,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C11H21NO3 · HCl
CAS Number:
Molecular Weight:
251.75
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 20 mg/mL, clear
storage temp.
room temp
SMILES string
CCCCCCOC(CCC(CN)=O)=O.[H]Cl
InChI
1S/C11H21NO3.ClH/c1-2-3-4-5-8-15-11(14)7-6-10(13)9-12;/h2-9,12H2,1H3;1H
InChI key
LZYXPFZBAZTOCH-UHFFFAOYSA-N
Biochem/physiol Actions
Hexaminolevulinate (HAL) hydrochloride is a hexyl ester of 5-Aminolevulinic acid (ALA), a precursor to porphyrins including the photosensitizer protoporphyrin IX (PPIX). Hexaminolevulinate is more lipophilic than ALA, and is 50–100 times more efficient than ALA at inducing PpIX, which accumulates preferentially in neoplastic cells. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancer, in particular carcinoma in situ (CIS). Hexaminolevulinate is also being studied for use in cancer photodynamic therapy. Hexaminolevulinate followed by irradiation produced DNA oxidative damage and apoptosis.
Hexaminolevulinate is a hexyl ester of 5-Aminolevulinic acid; imaging agen for fluorescence cyctoscopy; photosensitizer.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% | description BioReagent, suitable for cell culture, powder, ≥98% | description United States Pharmacopeia (USP) Reference Standard |
| assay ≥98% (HPLC) | assay ≥98% | assay ≥98% | assay - |
| form powder | form powder | form powder | form - |
| Quality Level 100 | Quality Level 300 | Quality Level 200 | Quality Level - |
| storage temp. room temp | storage temp. −20°C | storage temp. −20°C | storage temp. - |
| solubility H2O: 20 mg/mL, clear | solubility - | solubility H2O: 50 mg/mL | solubility - |
| storage condition desiccated | storage condition - | storage condition - | storage condition - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
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