SML1620
NGI-1
≥95% (HPLC), Asparagine (N)-linked glycoslysation inhibitor, powder
Synonym(s):
5-[(Dimethylamino)sulfonyl]-N-(5-methyl-2-thiazolyl)-2-(1-pyrrolidinyl)-benzamide, ML414
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 2 710,00 CZK |
25 mg | Please contact Customer Service for Availability | 10 900,00 CZK 9 265,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C17H22N4O3S2
CAS Number:
Molecular Weight:
394.51
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
powder
Product Name
NGI-1, ≥95% (HPLC)
Quality Segment
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
[S](=O)(=O)(N(C)C)c1cc(c(cc1)N3CCCC3)C(=O)Nc2[s]c(cn2)C
InChI key
QPKGRLIYJGBKJL-UHFFFAOYSA-N
Biochem/physiol Actions
NGI-1 (ML414) is an inhibitor of Asparagine (N)-linked glycoslysation.
NGI-1 (ML414) is an inhibitor of Asparagine (N)-linked glycoslysation. NGI-1 inhibits the oligosaccharyltransferase, preventing the attachment to the protein. NGI-1 has been shown to induce senescence in receptor tyrosine kinase dependent tumors.
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This Item | |||
|---|---|---|---|
| description ≥95% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| assay ≥95% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 5 mg/mL, clear (warmed) | solubility DMSO: >5 mg/mL | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 10 mg/mL, clear |
| color white to beige | color white to beige | color white to beige | color white to beige |
Storage Class
11 - Combustible Solids
WGK
WGK 3
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