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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 2 550,00 CZK 2 167,50 CZK |
25 mg | Please contact Customer Service for Availability | 10 400,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C16H14F3NO3S
CAS Number:
Molecular Weight:
357.35
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
2 167,50 CZK
List Price2 550,00 CZKSave 15%Web-Only Promotion
Please contact Customer Service for Availability
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
FC(F)(F)c1c2c(c(ccc2)C(=S)N(CC(=O)O)C)ccc1OC
InChI
1S/C16H14F3NO3S/c1-20(8-13(21)22)15(24)11-5-3-4-10-9(11)6-7-12(23-2)14(10)16(17,18)19/h3-7H,8H2,1-2H3,(H,21,22)
InChI key
LUBHDINQXIHVLS-UHFFFAOYSA-N
Biochem/physiol Actions
Tolrestat is an orally active and potent aldose reductase inhibitor. Studies have also shown that it reduces RBC (red blood cells) sorbitol levels in rats.
Tolrestat is considered to be effective in treating the consequences of diabetes including neuropathy, nephropathy, retinopathy and esophageal motility and vibration perception. Tolrestat is also believed to have lesser or no toxic effects.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level 100 |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 20 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility DMSO: ≥14 mg/mL |
| color white to beige | color white to beige | color white to beige | color white to tan |
Storage Class
11 - Combustible Solids
WGK
WGK 3
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