SML1444

(±)-Mepivacaine hydrochloride

≥98% (HPLC)

• Synonym(s): 1-Methyl-2,6-pipecoloxylidine hydrochloride, Carbocaine hydrochloride, N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride
• Empirical Formula (Hill Notation): C₁₅H₂₂N₂O · HCl
• CAS Number: 1722-62-9
• Molecular Weight: 282.81
• EC Number: 217-023-9
• MDL number: MFCD00144738
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825884
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: room temp
• InChI: 1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H
• InChI key: RETIMRUQNCDCQB-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Description

Biochem/physiol Actions

(±)-Mepivacaine hydrochloride is a local anesthetic that reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. (±)-Mepivacaine blocks tandem pore (TASK) and Kv1.5 potassium channels in model systems.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301,H336
• Precautionary Statements: P261 - P264 - P270 - P271 - P301 + P310 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable