This material dissolves clearly and colorlessly at 20 mg/mL in 0.05 M acetic acid. The product may appear as a powder or an oil film. This information is lot-specific and reported in the Certificate of Analysis. Please see the link below to access a sample or lot-specific Certificate:
https://www.sigmaaldrich.com/product/sigma/b4272#product-documentation
SML1418
AC187 trifluoroacetate salt
≥95% (HPLC)
Synonym(s):
AC 187, AC-187, Ac-VLGKLSQELHKLQTYPRTNTGSNTY-NH2, Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2, N-Acetyl-30-L-asparagine-32-L-tyrosinamide-8-32-calcitonin (salmon)
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| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Please contact Customer Service for Availability | 10 200,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C127H205N37O40 · xC2HF3O2
CAS Number:
Molecular Weight:
2890.21 (free base basis)
UNSPSC Code:
51111800
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
powder
Quality Segment
assay
≥95% (HPLC)
form
powder
color
white to off-white
shipped in
wet ice
storage temp.
−20°C
SMILES string
[nH]1cncc1C[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)C(C)C)CC(C)C)CCCCN)CC(C)C)CO)CCC(=O)N)CCC(=O)O)CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O
InChI
1S/C127H205N37O40/c1-59(2)44-81(156-122(200)99(63(9)10)142-68(15)171)105(183)139-54-96(178)143-74(22-16-18-40-128)106(184)151-84(47-62(7)8)114(192)159-90(57-166)119(197)148-77(34-37-92(130)174)108(186)146-79(36-39-98(180)181)109(187)153-83(46-61(5)6)113(191)154-85(50-71-53-137-58-141-71)115(193)145-75(23-17-19-41-129)107(185)152-82(45-60(3)4)112(190)147-78(35-38-93(131)175)111(189)162-103(67(14)170)125(203)158-88(49-70-28-32-73(173)33-29-70)126(204)164-43-21-25-91(164)120(198)149-76(24-20-42-138-127(135)136)110(188)161-102(66(13)169)124(202)157-87(52-95(133)177)117(195)160-100(64(11)167)121(199)140-55-97(179)144-89(56-165)118(196)155-86(51-94(132)176)116(194)163-101(65(12)168)123(201)150-80(104(134)182)48-69-26-30-72(172)31-27-69/h26-33,53,58-67,74-91,99-103,165-170,172-173H,16-25,34-52,54-57,128-129H2,1-15H3,(H2,130,174)(H2,131,175)(H2,132,176)(H2,133,177)(H2,134,182)(H,137,141)(H,139,183)(H,140,199)(H,142,171)(H,143,178)(H,144,179)(H,145,193)(H,146,186)(H,147,190)(H,148,197)(H,149,198)(H,150,201)(H,151,184)(H,152,185)(H,153,187)(H,154,191)(H,155,196)(H,156,200)(H,157,202)(H,158,203)(H,159,192)(H,160,195)(H,161,188)(H,162,189)(H,163,194)(H,180,181)(H4,135,136,138)/t64-,65-,66-,67-,74+,75+,76+,77+,78+,79+,80+,81+,82+,83+,84+,85+,86+,87+,88+,89+,90+,91+,99+,100+,101+,102+,103+/m1/s1
InChI key
ZLFXHYNEZYAYPG-AABHONRUSA-N
Biochem/physiol Actions
AC187 is an orally active, potent and selective amylin receptor antagonist that increases glucagon secretion, alters plasma glucose levels and increases food intake in vivo. AC187 completely blocks internalization of amylin monomers in pancreatic cells. AC187 blocks β-amyloid neurotoxicity in rats.
AC187 is an orally active, potent and selective amylin receptor antagonist.
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This Item | ||
|---|---|---|
| description ≥95% (HPLC) | description ≥95% (HPLC) | description ≥95% (HPLC) |
| form powder | form film | form powder |
| assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay ≥95% (HPLC) |
| Quality Level 100 | Quality Level - | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| color white to off-white | color white to beige | color white |
| shipped in wet ice | shipped in - | shipped in - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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