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(−)-Nicotine hydrogen tartrate salt

Name: (&#8722;)-Nicotine hydrogen tartrate salt
Brand: SIGMA
Price: 2160 CZK

≥98% (HPLC), acetylcholine receptor agonist, powder

Synonym(s):

(−)-Nicotine ditartrate, (−)-1-Methyl-2-(3-pyridyl)pyrrolidine (+)-bitartrate salt

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Size/SKU	Availability	Price
50 mg	Please contact Customer Service for Availability	2 160,00 CZK
1 g	Please contact Customer Service for Availability	34 600,00 CZK

About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₄N₂ · 2C₄H₆O₆

CAS Number:

65-31-6

Molecular Weight:

462.41

UNSPSC Code:

12352210

PubChem Substance ID:

329825736

NACRES:

NA.77

EC Number:

200-607-2

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

desiccated

2 160,00 CZK

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Properties

Product Name

(−)-Nicotine hydrogen tartrate salt, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D +20 to +26°, c = 1.0 in water

storage condition

desiccated

color

white to beige

solubility

H₂O: 20 mg/mL, clear

storage temp.

room temp

SMILES string

CN1CCC[C@H]1C2=CC=CN=C2.C

InChI

1S/C10H14N2.CH4/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;/h2,4,6,8,10H,3,5,7H2,1H3;1H4/t10-;/m0./s1

InChI key

RYYKFQGHMYGLEL-PPHPATTJSA-N

Description

Application

(−)-Nicotine hydrogen tartrate salt has been used in intracellular calcium imaging.

(−)-Nicotine hydrogen tartrate salt has been used as an agonist for acetylcholine receptor (AChr).

Biochem/physiol Actions

Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer.

NHT is considered to be more stable than nicotine. Nicotine is highly addictive drug and is indirectly but strongly associated with tobacco related diseases. It helps to discontinue smoking. Nicotine might serve as a therapeutic agent in treating Alzheimer’s disease, Parkinson’s disease and ulcerative colitis.

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1 of 1

This Item	N0590200	PHL80224	Y0001023
Sigma-Aldrich SML1236 (−)-Nicotine hydrogen tartrate salt	N0590200 Nicotine ditartrate	PHL80224 Nicotine ditartrate	Y0001023 Nicotine for system suitability
description ≥98% (HPLC)	description European Pharmacopoeia (EP) Reference Standard	description phyproof^® Reference Substance	description European Pharmacopoeia (EP) Reference Standard
assay ≥98% (HPLC)	assay -	assay ≥95.0% (HPLC)	assay -
form powder	form -	form solid	form -
Quality Level 100	Quality Level -	Quality Level -	Quality Level -
storage temp. room temp	storage temp. -	storage temp. -	storage temp. −20°C
storage condition desiccated	storage condition -	storage condition -	storage condition -
solubility H₂O: 20 mg/mL, clear	solubility -	solubility -	solubility -

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Pictograms

GHS06,GHS08,GHS09

Signal Word

Danger

Hazard Codes

H301,H319,H330,H361d,H411

Precautionary Statements

P202 - P260 - P264 - P273 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

Flash Point (°F)

289.8 °F

Flash Point (°C)

143.2 °C

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