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SML1200

RO8191

≥98% (HPLC)

Synonym(s):

8-(1,3,4-Oxadiazol-2-yl)-2,4-bis(trifluoromethyl)-imidazo[1,2-a][1,8]naphthyridine, RO4948191

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Size/SKUAvailabilityPrice
25 mg
Please contact Customer Service for Availability
11 500,00 CZK

About This Item

Empirical Formula (Hill Notation):
C14H5F6N5O
CAS Number:
Molecular Weight:
373.21
UNSPSC Code:
51111800
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

11 500,00 CZK


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 0.5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

FC(F)(F)c1nc2[n]3c(nc(c3)c4nnc[o]4)ccc2c(c1)C(F)(F)F

InChI key

GRHYZVJEXKTJOS-UHFFFAOYSA-N

Biochem/physiol Actions

RO8191 is a potent and specific type I interferon receptor agonist that directly binds to IFN-α receptor 2 (IFNAR2).
RO8191 is an orally available, potent and specific type I interferon receptor agonist that directly binds to IFN-α receptor 2 (IFNAR2). RO8191 suppresses HCV replication without inducing host cell toxicity.
RO8191 is an imidazonaphthyridine compound, which activates interferon (IFN) signals, IFN-stimulated genes (ISGs) expression and Janus kinase (JAK)/signal transducers and activators of transcription (STAT) phosphorylation.

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ZRB2139EMU032741SAB1401203
description

≥98% (HPLC)

description

recombinant, expressed in HEK 293 cells

description

targeting mouse Ifnar2

description

purified immunoglobulin, buffered aqueous solution

assay

≥98% (HPLC)

assay

-

assay

-

assay

-

form

powder

form

lyophilized

form

lyophilized powder

form

buffered aqueous solution

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: 0.5 mg/mL, clear (warmed)

solubility

-

solubility

-

solubility

-

color

white to beige

color

-

color

-

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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