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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 3 050,00 CZK |
25 mg | Please contact Customer Service for Availability | 12 100,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C23H25BF2N2O2
CAS Number:
Molecular Weight:
410.26
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
, dark blue to black
solubility
DMSO: 0.2 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
[B-]1([O+]=C(C=C(O1)\C=C\c3ccc(cc3)N(C)C)\C=C\c2ccc(cc2)N(C)C)(F)F
InChI
1S/C23H25BF2N2O2/c1-27(2)20-11-5-18(6-12-20)9-15-22-17-23(30-24(25,26)29-22)16-10-19-7-13-21(14-8-19)28(3)4/h5-17H,1-4H3/b15-9+,16-10+
InChI key
PVXQJYXODFZTBR-KAVGSWPWSA-N
Biochem/physiol Actions
CRANAD 2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe.
CRANAD 2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM. Upon interacting with Aβ aggregates, CRANAD 2 exhibits a 70-fold increase in fluorescence intensity accompanied by a 90 nm blue shift from 805 to 715 nm and a large increase in quantum yield. CRANAD 2 has been used to detect Aβ deposits noninvasively in vivo in transgenic Tg2576 mice.
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This Item | |
|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 0.2 mg/mL, clear (warmed) | solubility DMSO: 2 mg/mL, clear (warmed) |
| storage condition desiccated | storage condition desiccated |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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