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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Please contact Customer Service for Availability | 3 070,00 CZK 2 609,50 CZK |
25 mg | Please contact Customer Service for Availability | 12 000,00 CZK 10 200,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C8H14CuN6S2
CAS Number:
Molecular Weight:
321.91
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
2 609,50 CZK
List Price3 070,00 CZKSave 15%Web-Only Promotion
Please contact Customer Service for Availability
Product Name
Cu-ATSM, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
, brown to dark red-brown
solubility
DMSO: 0.5 mg/mL, clear (warmed)
storage temp.
2-8°C
Biochem/physiol Actions
Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that specifically inhibits the action of peroxynitrite on Cu,Zn superoxide dismutase (SOD1) and subsequent nitration of cellular proteins. CuII(ATSM) significantly delayed onset of disease (paralysis and prolonged lifespan) in amyotrophic lateral sclerosis (ALS) mice model. Also, Cu-ATSM was reported to lower lipid peroxidation in a model of ischemicreperfusion injury. Cu-ATSM subsequently was shown to inhibit ferroptosis with a potency similar to Liproxstatin-1.
Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that specifically inhibits the action of peroxynitrite on Cu,Zn superoxide dismutase (SOD1).
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥97% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC), powder |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥97% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 0.5 mg/mL, clear (warmed) | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear (Warmed) | solubility DMSO: 18 mg/mL, H2O: insoluble |
| color , brown to dark red-brown | color dark green to black | color , Faint brown to dark red | color - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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