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SML0769

Cu-ATSM

≥98% (HPLC), peroxynitrite inhibitor, powder

Synonym(s):

CuII(ATSM), Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II), [[2,2′-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]] copper

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
3 070,00 CZK
2 609,50 CZK
25 mg
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12 000,00 CZK
10 200,00 CZK

About This Item

Empirical Formula (Hill Notation):
C8H14CuN6S2
CAS Number:
Molecular Weight:
321.91
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

2 609,50 CZK

List Price3 070,00 CZKSave 15%
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Product Name

Cu-ATSM, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

, brown to dark red-brown

solubility

DMSO: 0.5 mg/mL, clear (warmed)

storage temp.

2-8°C

Biochem/physiol Actions

Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that specifically inhibits the action of peroxynitrite on Cu,Zn superoxide dismutase (SOD1) and subsequent nitration of cellular proteins. CuII(ATSM) significantly delayed onset of disease (paralysis and prolonged lifespan) in amyotrophic lateral sclerosis (ALS) mice model. Also, Cu-ATSM was reported to lower lipid peroxidation in a model of ischemicreperfusion injury. Cu-ATSM subsequently was shown to inhibit ferroptosis with a potency similar to Liproxstatin-1.
Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that specifically inhibits the action of peroxynitrite on Cu,Zn superoxide dismutase (SOD1).

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This Item
SML2675SML3488B9935
description

≥98% (HPLC)

description

≥97% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC), powder

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥97% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 0.5 mg/mL, clear (warmed)

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear (Warmed)

solubility

DMSO: 18 mg/mL, H2O: insoluble

color

, brown to dark red-brown

color

dark green to black

color

, Faint brown to dark red

color

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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