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SML0752

(+)-CP-99994 dihydrochloride

≥98% (HPLC), neurokinin (NK)-1 tachykinin antagonist, powder

Synonym(s):

(2S,3S)-3-(2-Methoxybenzylamino)-2-phenylpiperidine dihydrochloride, CP-99,994, CP-99994, CP99,994, CP99994

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
3 710,00 CZK
25 mg
Please contact Customer Service for Availability
13 400,00 CZK
11 390,00 CZK

About This Item

Empirical Formula (Hill Notation):
C19H24N2O · 2HCl
CAS Number:
Molecular Weight:
369.33
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

3 710,00 CZK


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Product Name

(+)-CP-99994 dihydrochloride, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 15 mg/mL, clear

storage temp.

2-8°C

SMILES string

[Cl-].[Cl-].[N+H2]1[C@H]([C@H](CCC1)[N+H2]Cc3c(cccc3)OC)c2ccccc2

InChI

1S/C19H24N2O.2ClH/c1-22-18-12-6-5-10-16(18)14-21-17-11-7-13-20-19(17)15-8-3-2-4-9-15;;/h2-6,8-10,12,17,19-21H,7,11,13-14H2,1H3;2*1H/t17-,19-;;/m0../s1

InChI key

WNHRFWPLRATIDT-FFUVTKDNSA-N

Biochem/physiol Actions

(+)-CP-99994 is a selective neurokinin (NK)-1 tachykinin antagonist.
(+)-CP-99994 is a selective neurokinin (NK)-1 tachykinin antagonist. (+)-CP-99994 binds selectively and with high affinity with a Ki of 0.25 nM in a human cell line.
(+)-CP-99994 dihydrochloride is an effective and selective non-peptide substance P receptor antagonist. It is synthesized from allylic and homoallylic C-H diamination of 4-phenyl-1-butene. (+)-CP-99994 exhibits anti-emetic activity in ferrets.

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This Item
SML0588SML0667PZ0136
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥97% (HPLC)

form

powder

form

powder

form

powder

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

storage temp.

room temp

storage condition

desiccated

storage condition

desiccated

storage condition

desiccated

storage condition

-

solubility

H2O: 15 mg/mL, clear

solubility

H2O: 15 mg/mL, clear

solubility

H2O: 15 mg/mL, clear

solubility

H2O: ≥5 mg/mL


pictograms

Environment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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