Skip to Content
Merck

Key Documents

View All Documentation

Skip To

SML0698

CID 11210285 hydrochloride

≥98% (HPLC)

Synonym(s):

2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine hydrochloride, AMBMP, N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine hydrochloride, Wnt Agonist

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
2 980,00 CZK
2 533,00 CZK
25 mg
Please contact Customer Service for Availability
9 630,00 CZK

About This Item

Empirical Formula (Hill Notation):
C19H18N4O3 · HCl
CAS Number:
853220-52-7
Molecular Weight:
386.83
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

2 533,00 CZK

List Price2 980,00 CZKSave 15%
Web-Only Promotion
Please contact Customer Service for Availability
​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

N(Cc3cc4c(cc3)OCO4)c1nc(nc(c1)c2cc(ccc2)OC)N

InChI

1S/C19H18N4O3/c1-24-14-4-2-3-13(8-14)15-9-18(23-19(20)22-15)21-10-12-5-6-16-17(7-12)26-11-25-16/h2-9H,10-11H2,1H3,(H3,20,21,22,23)

InChI key

FABQUVYDAXWUQP-UHFFFAOYSA-N

Application

CID 11210285 hydrochloride has been used as a Wnt agonist.

Biochem/physiol Actions

CID 11210285 is a cell-permeable, potent and selective activator of Wnt signaling without inhibiting GSK-3β.
CID 11210285 is a cell-permeable, potent and selective activator of Wnt signaling without inhibiting GSK-3β. CID 11210285is a Wnt agonist.

Other Notes

Light sensitve and air sensitive.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
681664SML1552L6670
CID 11210285 hydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML0698

CID 11210285 hydrochloride

Wnt Agonist I in DMSO The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.

Sigma-Aldrich

681664

Wnt Agonist I in DMSO

Tipiracil hydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML1552

Tipiracil hydrochloride

LY266097 ≥98% (HPLC), powder

Sigma-Aldrich

L6670

LY266097

description

≥98% (HPLC)

description

The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.

description

≥98% (HPLC)

description

≥98% (HPLC), powder

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

liquid

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

−70°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

protect from light, OK to freeze, desiccated (hygroscopic), avoid repeated freeze/thaw cycles

storage condition

desiccated

storage condition

desiccated

solubility

DMSO: 20 mg/mL, clear

solubility

-

solubility

H2O: 5 mg/mL, clear (warmed)

solubility

DMSO: ≥20 mg/mL

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Codes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

  1. What other vehicles can be used for the administration of the agonist in a mouse model? It can be administered locally (bone tissue) or only systemically?

    1 answer

    1. This product has not been tested for in vivo or in vitro applications. The method of administration will need to be validated by the end user. It may be helpful to view peer-reviewed articles. Please see the two publications below :

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662016/
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8565963/

      Helpful?

Reviews

No rating value

Active Filters