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SML0558

BETP

≥98% (HPLC)

Synonym(s):

2-(Ethylsulfinyl)-4-[3-(phenylmethoxy)phenyl]-6-(trifluoromethyl)-pyrimidine

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
3 650,00 CZK
3 102,50 CZK
25 mg
Please contact Customer Service for Availability
13 700,00 CZK

About This Item

Empirical Formula (Hill Notation):
C20H17F3N2O2S
CAS Number:
Molecular Weight:
406.42
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

3 102,50 CZK

List Price3 650,00 CZKSave 15%
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

CCS(=O)c1nc(cc(n1)C(F)(F)F)-c2cccc(OCc3ccccc3)c2

InChI

1S/C20H17F3N2O2S/c1-2-28(26)19-24-17(12-18(25-19)20(21,22)23)15-9-6-10-16(11-15)27-13-14-7-4-3-5-8-14/h3-12H,2,13H2,1H3

InChI key

NTDFYGSSDDMNHI-UHFFFAOYSA-N

Biochem/physiol Actions

BETP is a GLP-1 receptor allosteric modulator.
BETP is a positive allosteric modulator of the GLP-1 receptor that potentiates cAMP accumulation and glucose-dependent insulin release in pancreatic islet cells, in the presence of the weak GLP-1 metabolite, GLP-1(9-36). BETP has additive effects on the endogenous GLP-1 receptor ligand GLP-1(7-36).
BetP is a trimeric Na+-coupled betaine symporter. BetP belongs to the betaine-choline-carnitine transporter (BCCT) family. It controls transport activity in dependence of the cytoplasmic K+-concentration.

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This Item
346007B2754PHR2355
description

≥98% (HPLC)

description

-

description

≥99%

description

Pharmaceutical Secondary Standard; Certified Reference Material

form

powder

form

solid

form

powder or crystals

form

powder

assay

≥98% (HPLC)

assay

>95% (HPLC)

assay

≥99%

assay

-

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

300

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-30°C

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: 100 mg/mL

solubility

water: 50 mg/mL, clear, colorless

solubility

-

color

white to beige

color

off-white

color

-

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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