SML0397
DR2313
≥98% (HPLC)
Synonym(s):
3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one
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About This Item
Empirical Formula (Hill Notation):
C8H10N2OS
CAS Number:
Molecular Weight:
182.24
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
To inquire about this product SML0397, please contact your local Merck office or dealer. Contact Technical Service
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
H2O: >2 mg/mL (warmed)
storage temp.
2-8°C
SMILES string
CC1=NC(=O)C2=C(CCSC2)N1
InChI
1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11)
InChI key
HRYKZAKEAVZGJD-UHFFFAOYSA-N
Biochem/physiol Actions
DR2313 is a PARP inhibitor.
DR2313 is a PARP-1; PARP-2 inhibitor (Ki = 0.23 mM). DR2313 has neuroprotective effects in both in vivo and in vitro ischemic models, and reduces cortical infarct volume in focal ischemia in rats.
Features and Benefits
This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility H2O: >2 mg/mL (warmed) | solubility DMSO: >28 mg/mL (warmed) | solubility DMSO: 13 mg/mL | solubility DMSO: 2 mg/mL, clear (warmed) |
| color white to beige | color white to off-white | color white | color yellow to orange |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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