SML0351

CPDT

≥96% (HPLC)

• Synonym(s): 5,6-Dihydro-Cyclopenta[c]-1,2-dithiole-3(4H)-thione, CJ 11788, SNU2A
• Empirical Formula (Hill Notation): C₆H₆S₃
• CAS Number: 14085-33-7
• Molecular Weight: 174.31
• NACRES: NA.77
• PubChem Substance ID: 329825354
• UNSPSC Code: 12352200
• MDL number: MFCD00799281
• Assay: ≥96% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥96% (HPLC)
• form: powder
• color: faintly red to very dark red
• solubility: DMSO: 2 mg/mL (warmed)
• storage temp.: 2-8°C
• SMILES string: S=C1SSC2=C1CCC2
• InChI: 1S/C6H6S3/c7-6-4-2-1-3-5(4)8-9-6/h1-3H2
• InChI key: AVSGTGUIBQOXJK-UHFFFAOYSA-N

Description

Application

5,6-dihydrocyclopenta-1,2-dithiole-3-thione (CPDT) has been used to study its protective effects and the underlying mechanism in diabetic cardiomyopathy.

Biochem/physiol Actions

CPTD (SNU2A) is a cytoprotective agent that protects mitochondria during cell stress by increasing antioxidant capacity. CPTD inhibits phosphorylation and activation of Fyn, which maintains AMPK activity and activation of Nrf2.

CPTD is an anti-oxidant, cytoprotective agent.

5,6-dihydrocyclopenta-1,2-dithiole-3-thione (CPDT) is a phase II enzyme inducer. It exhibits protective actions against chemical carcinogens.

Safety Information

• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• Hazard Codes: H412
• Precautionary Statements: P273 - P501
• Hazard Classifications: Aquatic Chronic 3
• Storage Class: 13 - Non Combustible Solids