SML0295

Dihydromyricetin

≥98% (HPLC)

• Synonym(s): (2R,3R)-3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one, 3,3′,4′,5,5′,7-Hexahydroxyflavanone, Ampelopsin, Ampeloptin, DHM
• Empirical Formula (Hill Notation): C₁₅H₁₂O₈
• CAS Number: 27200-12-0
• Molecular Weight: 320.25
• NACRES: NA.77
• PubChem Substance ID: 329825302
• UNSPSC Code: 12352200
• MDL number: MFCD00189451
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: protect from light

Properties

• assay: ≥98% (HPLC)
• form: powder
• storage condition: protect from light
• color: white to beige
• solubility: DMSO: ≥5 mg/mL (warmed)
• storage temp.: −20°C
• SMILES string: O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(O)=C(C(O)=C3)O)[C@H]1O
• InChI: 1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1
• InChI key: KJXSIXMJHKAJOD-LSDHHAIUSA-N

Description

General description

Dihydromyricetin is a major flavonoid present in A. grossedentata.

Application

Dihydromyricetin has been used to study its effect on adipogenesis and glucose uptake in differentiated 3T3-L1 pre-adipocytes. It has also been used to study its antitumor activity against liver cancer cells.

Biochem/physiol Actions

Dihydromyricetin (Ampelopsin) is a flavanonol with antioxidant and anti-cancer activity, found to have anti-alcohol intoxication effects. Its anti-alcohol effects appear to be by its actions as a positive modulator of GABA-A receptors at the benzodiazepine site.

Dihydromyricetin (Ampelopsin) is a flavanonol with antioxidant and anti-cancer activity.

Dihydromyricetin possesses anti-inflammatory action.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable