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SML0293

Telbivudine

≥98% (HPLC)

Synonym(s):

β-L-Thymidine, 1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-Pyrimidinedione, 2′-Deoxy-L-thymidine, Epavudine, L-Thymidine, NV 02B, Sebivo

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
3 250,00 CZK
25 mg
Please contact Customer Service for Availability
12 200,00 CZK

About This Item

Empirical Formula (Hill Notation):
C10H14N2O5
CAS Number:
3424-98-4
Molecular Weight:
242.23
NACRES:
NA.77
PubChem Substance ID:
329825300
UNSPSC Code:
12352200
MDL number:
MFCD02683612
Assay:
≥98% (HPLC)
Form:
powder

3 250,00 CZK

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Quality Segment

100

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -15 to -22°, c = 1 in H2O

color

white to beige

solubility

H2O: 10 mg/mL (clear solution)

storage temp.

2-8°C

SMILES string

CC1=CN([C@@H]2C[C@@H](O)[C@H](CO)O2)C(=O)NC1=O

InChI

1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1

InChI key

IQFYYKKMVGJFEH-CSMHCCOUSA-N

Application

Telbivudine has been used to explore the mechanisms of telbivudine (LdT) induced creatine kinase (CK) elevation.[1]

Biochem/physiol Actions

Telbivudine is a nucleoside analog that is widely used to treat hepatitis B virus (HBV) infection.
Telbivudine is a synthetic molecule[2] containing β-L-configuration.[1] Telbivudine improves the estimated glomerular filtration rate (eGFR) in response to chronic hepatitis B (CHB). It prevents perinatal transmission and enhances the hepatitis B e antigen (HBeAg) seroconversion. It is also known to cause side effects such as creatine kinase (CK) elevation and fatal rhabdomyolysis.[1]
Telbivudineis a Hepatitis B antiviral agent.

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This Item
SML1296D1413SML1836
Telbivudine ≥98% (HPLC)

Sigma-Aldrich

SML0293

Telbivudine

6-Thio-2′-Deoxyguanosine ≥97% (HPLC)

Sigma-Aldrich

SML1296

6-Thio-2′-Deoxyguanosine

2′,3′-Didehydro-3′-deoxythymidine ≥98% (TLC)

Sigma-Aldrich

D1413

2′,3′-Didehydro-3′-deoxythymidine

β-ODAP ≥98% (HPLC)

Sigma-Aldrich

SML1836

β-ODAP

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥97% (HPLC)

assay

≥98% (TLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

H2O: 10 mg/mL (clear solution)

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

-

solubility

0.1 M HCl: 2 mg/mL, clear (warmed)

color

white to beige

color

white to brown

color

-

color

white to beige

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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