SML0258

CPPG

≥98% (HPLC)

• Synonym(s): (R,S)-α-Cyclopropyl-4-phosphonophenylglycine
• Empirical Formula (Hill Notation): C₁₁H₁₄NO₅P
• CAS Number: 183364-82-1
• Molecular Weight: 271.21
• NACRES: NA.77
• PubChem Substance ID: 329825266
• UNSPSC Code: 12352200
• MDL number: MFCD00673967
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Properties

• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: >5 mg/mL
• storage temp.: room temp
• SMILES string: NC(C1CC1)(C(O)=O)c2ccc(cc2)P(O)(O)=O
• InChI: 1S/C11H14NO5P/c12-11(10(13)14,7-1-2-7)8-3-5-9(6-4-8)18(15,16)17/h3-7H,1-2,12H2,(H,13,14)(H2,15,16,17)
• InChI key: IGODGTDUQSMDQU-UHFFFAOYSA-N

Description

Biochem/physiol Actions

CPPG is a potent group II/III metabotropic glutamate receptor antagonist, with approximately 20-fold selectivity for mGlu group III over group II (IC₅₀ values of 2.2 and 46.2 nM respectively).

CPPG is a potent group II/III metabotropic glutamate receptor antagonist.

(R,S)-α-Cyclopropyl-4-phosphonophenylglycine (CPPG) can be used in combination with scopolamine to treat the depressive disorder.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable