SML0235

CDPPB

≥98% (HPLC)

• Synonym(s): 3-Cyano-N-1,3-diphenyl-1H-pyrazol-5-yl)benzamide
• Empirical Formula (Hill Notation): C₂₃H₁₆N₄O
• CAS Number: 781652-57-1
• Molecular Weight: 364.40
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825248
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: ≥5 mg/mL at warmed to 60 °C
• storage temp.: 2-8°C
• SMILES string: O.O=C(Nc1cc(nn1-c2ccccc2)-c3ccccc3)c4cccc(c4)C#N
• InChI: 1S/C23H16N4O.H2O/c24-16-17-8-7-11-19(14-17)23(28)25-22-15-21(18-9-3-1-4-10-18)26-27(22)20-12-5-2-6-13-20;/h1-15H,(H,25,28);1H2
• InChI key: GZHZEGYXLNXEBV-UHFFFAOYSA-N

Description

Application

CDPPB may be used in mGluR5-mediated cell signaling studies.

Biochem/physiol Actions

CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator.

CDPPB is an mGluR5 positive allosteric modulator

Activation of metabotropic glutamate 5 receptor by CDPPB enhances the function of NMDA receptor and markers of neuronal plasticity. This improves recognition memory and cognition deficits in schizophrenia.

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable