SML0045

Salvianolic acid A hydrate

≥98% (HPLC)

• Synonym(s): Dan phenolic acid A hydrate
• Empirical Formula (Hill Notation): C₂₆H₂₂O₁₀ · xH₂O
• CAS Number: 96574-01-5
• Molecular Weight: 494.45 (anhydrous basis)
• MDL number: MFCD20527310
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825115
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: yellow
• solubility: H₂O: ≥19 mg/mL
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: O.OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2\C=C\c3ccc(O)c(O)c3
• InChI: 1S/C26H22O10.H2O/c27-18-7-2-14(11-21(18)30)1-6-17-16(4-9-20(29)25(17)33)5-10-24(32)36-23(26(34)35)13-15-3-8-19(28)22(31)12-15;/h1-12,23,27-31,33H,13H2,(H,34,35);1H2/b6-1+,10-5+;/t23-;/m1./s1
• InChI key: XFUSRNNWIRPEDG-FYLUTCCGSA-N

Description

Application

Salvianolic acid A hydrate may be used in cell signaling studies.
Salvianolic acid A hydrate has been used as rosmarinic acid derivative for the inhibition of DNA polymerase e in human cell lines.

Biochem/physiol Actions

Salvianolic acid A acts as scavengers of reactive oxygen species, reduces the adherence of leukocytes to endothelial cells, inhibits matrix metalloproteinases and inflammation. It has cardioprotective effects as it suppresses apoptosis, reduces lipid peroxidation in damaged cardiac tissue and decreases the leakage of lactic acid dehydrogenase.

Salvianolic acid A is cell protective antioxidant originally isolated from Salvia. It has been found to attenuate PDGF-induced ROS formation in hepatic stellate cells and protected against isoproterenol-induced myocardial damage in rats.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable