SML0043

Racecadotril

≥98% (HPLC)

• Synonym(s): (RS)-Benzyl N-[3-(acetylthio)-2-benzylpropanoyl]glycinate, (±)-Acetorphan, Acetorphan, Cadotril, Redotil, Tiorfan, Zedott
• Empirical Formula (Hill Notation): C₂₁H₂₃NO₄S
• CAS Number: 81110-73-8
• Molecular Weight: 385.48
• NACRES: NA.77
• PubChem Substance ID: 329825113
• UNSPSC Code: 12352200
• MDL number: MFCD00865520
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: ≥44 mg/mL
• storage temp.: room temp
• SMILES string: CC(=O)SCC(Cc1ccccc1)C(=O)NCC(=O)OCc2ccccc2
• InChI: 1S/C21H23NO4S/c1-16(23)27-15-19(12-17-8-4-2-5-9-17)21(25)22-13-20(24)26-14-18-10-6-3-7-11-18/h2-11,19H,12-15H2,1H3,(H,22,25)
• InChI key: ODUOJXZPIYUATO-UHFFFAOYSA-N

Description

Application

Racecadotril may be used to study enkephalinase-mediated cellular changes.

Biochem/physiol Actions

Neutral endopeptidase inhibitor; antidiarrheal

Racecadotril is a neutral endopeptidase inhibitor, an antidiarrheal drug which acts as a peripherally acting enkephalinase inhibitor.

Inhibition of enkephalinase by Racecadotril prevents the breakdown of enkephalins in the gastrointestinal tract. This reduces secretion of water and electrolytes into the gut without affecting the mobility.

Features and Benefits

This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Codes: H302,H400
• Precautionary Statements: P273 - P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable