This product is a research grade Itopride and not considered a primary or secondary standard. Currently, there is no primary standard product available.
SML0033
Itopride hydrochloride
≥98% (HPLC), dopamine D2-receptor antagonist, powder
Synonym(s):
N-[[4-[2-(Dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy benzamidehydrochloride, N-[p-[2-(dimethylamino)ethoxy]benzyl]veratramide hydrochloride
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| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Please contact Customer Service for Availability | 2 930,00 CZK |
50 mg | Please contact Customer Service for Availability | 11 500,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C20H26N2O4 ·HCl
CAS Number:
Molecular Weight:
394.89
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Product Name
Itopride hydrochloride, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to tan
solubility
H2O: ≥48 mg/mL
originator
Abbott
storage temp.
2-8°C
SMILES string
Cl.COc1ccc(cc1OC)C(=O)NCc2ccc(OCCN(C)C)cc2
InChI
1S/C20H26N2O4.ClH/c1-22(2)11-12-26-17-8-5-15(6-9-17)14-21-20(23)16-7-10-18(24-3)19(13-16)25-4;/h5-10,13H,11-12,14H2,1-4H3,(H,21,23);1H
InChI key
ZTOUXLLIPWWHSR-UHFFFAOYSA-N
General description
Itopride hydrochloride is a new prokinetic drug.
Biochem/physiol Actions
Antagonist of dopamine D2-receptor with anticholinesterase activity.
Itopride is an acetylcholinesterase (AChE) inhibitor and D2 dopamine receptor antagonist. Itopride is used as a gastroprokinetic agent.
Itopride hydrochloride enhances the gastrointestinal motility by blocking the activity of dopamine on the D2 receptors, on the post-synaptic cholinergic nerves and by inducing the liberation of acetylcholine in the myenteric plexus. It also inhibits the hydrolysis of the released acetylcholine with the help of acetylcholinesterase.
Features and Benefits
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC), powder |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility H2O: ≥48 mg/mL | solubility DMSO: ≥15 mg/mL | solubility H2O: 2 mg/mL, clear (warmed) | solubility H2O: >10 mg/mL |
| storage condition desiccated | storage condition - | storage condition desiccated | storage condition desiccated |
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Is the Itopride HCL CAS 122892-31-3 a primary standard grade or a reagent grade?
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