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SCP0158

Granzyme B Substrate

≥95% (HPLC), lyophilized

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5 mg
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5 310,00 CZK

About This Item

Empirical Formula (Hill Notation):
C32H41N5O11
Molecular Weight:
671.69
UNSPSC Code:
12352204
NACRES:
NA.32

5 310,00 CZK

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Product Name

Granzyme B Substrate,

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥85%

storage condition

protect from light

storage temp.

−20°C

Application

Granzyme B Substrate (Ac-IEPD-AMC) is a fluorogenic substrate for the detection and assay of caspase 8 and granzyme B which is involved in the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Biochem/physiol Actions

Granzymes belongs to serine proteinase family enzymes and it localizes along with perforin in granules. It is predominant in cytotoxic T cells. Granzyme B induces caspases dependent and independent cell death. It possesses specific cleavage action at aspartate residue in the substrate.

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This Item
SRP3202368057SRE0021
description

-

description

recombinant, expressed in Hi-5 Insect cells, ≥97% (SDS-PAGE), ≥97% (HPLC), suitable for cell culture

description

Colorimetric substrate for the detection of granzyme B and caspase-8 activity.

description

recombinant, expressed in insect cells, ≥90% (SDS-PAGE)

assay

≥95% (HPLC)

assay

≥97% (HPLC), ≥97% (SDS-PAGE)

assay

≥95% (HPLC)

assay

≥90% (SDS-PAGE)

form

lyophilized

form

lyophilized

form

lyophilized solid

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−70°C

storage condition

protect from light

storage condition

-

storage condition

OK to freeze, protect from light

storage condition

-

composition

Peptide Content, ≥85%

composition

-

composition

-

composition

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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