SCP0002
Acetyl-Amyloid β 25-35
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| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Please contact Customer Service for Availability | 2 430,00 CZK |
About This Item
Empirical Formula (Hill Notation):
C47H83N13O15S1
Molecular Weight:
1102.31
NACRES:
NA.32
UNSPSC Code:
12352202
General description
Amyloid-β (Aβ) peptides are a major component of the senile plaques characteristic of the Alzheimer brain. It is a type- I transmembrane protein. The amyloid β precursor protein is cleaved to amyloid peptides 36-43 amino acids in length. Aβ (25-35) represents the region that aggregates during plaque formation and is a functional domain implicated in both neurotrophic and neurotoxic effects. The gene encoding amyloid-β is localized on human chromosome 21. Acetylation may improve stability in in vitro and in vivo assays.
Application
Acetyl-Amyloid β 25-35 has been used to prepare rat models with Alzheimer′s disease.
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This Item | |||
|---|---|---|---|
| description - | description ≥95% (HPLC) | description ≥95% (HPLC) | description - |
| assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay >97.0% |
| form lyophilized | form lyophilized | form powder | form (Clear dry film) |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. - |
| storage condition protect from light | storage condition protect from light | storage condition - | storage condition - |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| Gene Information human ... APP(351) | Gene Information human ... APP(351) | Gene Information human ... APP(351) | Gene Information human ... APP(351) |
![[Gly22]-Amyloid β 1-40 Arctic human ≥95% (HPLC)](/deepweb/assets/sigmaaldrich/product/images/323/896/73f7f5ce-ef84-4036-84bc-ad1606488d26/640/73f7f5ce-ef84-4036-84bc-ad1606488d26.jpg)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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