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| Size/SKU | Availability | Price |
|---|---|---|
1 mL | Please contact Customer Service for Availability | 3 920,00 CZK |
About This Item
NACRES:
NA.54
UNSPSC Code:
12352204
Form:
ready-to-use solution
3 920,00 CZK
Please contact Customer Service for Availability
General description
E-64 is a cysteine protease inhibitor that effectively inhibits various cysteine proteases such as: cathepsin K, cathepsin L, cathepsin S known also as N-[N-(L-3-trans-carboxyoxiran-2-carbonyl)-L-leucyl]-agmatine, E-64 was isolated from the mold Aspergillus japonicus TPR-64.
Biochem/physiol Actions
E-64 is an highly selective, potent and irreversible cysteine protease inhibitor. The trans-epoxysuccinyl group of E-64 is its active moiety, and irreversibly binds to an active thiol group of many cysteine proteases, such as papain, actinidase, and cathepsins B, H and L, to form a thioether linkage.
Preparation Note
This E-64 Ready Made Solution is supplied as a proprietary 2.8 mM non-freezing solution formulation.
1 of 1
This Item | |||
|---|---|---|---|
| description Non-freezing solution, 1 mg/mL | description suitable for cell culture | description 50 mg/mL in DMSO/H2O, 1:1 | description ≥98% (HPLC), 7.5mg/ml (50mM) in MES buffer, Autophagy inhibitor |
| form ready-to-use solution | form solution | form liquid (1:1 DMSO:H2O) | form liquid |
| Quality Level 200 | Quality Level - | Quality Level 200 | Quality Level - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| shipped in wet ice | shipped in dry ice | shipped in dry ice | shipped in ambient |
Storage Class
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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