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SAE0154

E64 Ready Made solution

Non-freezing solution, 1 mg/mL

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Size/SKUAvailabilityPrice
1 mL
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3 920,00 CZK

About This Item

NACRES:
NA.54
UNSPSC Code:
12352204
Form:
ready-to-use solution

3 920,00 CZK


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Quality Segment

form

ready-to-use solution

shipped in

wet ice

storage temp.

−20°C

General description

E-64 is a cysteine protease inhibitor that effectively inhibits various cysteine proteases such as: cathepsin K, cathepsin L, cathepsin S known also as N-[N-(L-3-trans-carboxyoxiran-2-carbonyl)-L-leucyl]-agmatine, E-64 was isolated from the mold Aspergillus japonicus TPR-64.

Biochem/physiol Actions

E-64 is an highly selective, potent and irreversible cysteine protease inhibitor. The trans-epoxysuccinyl group of E-64 is its active moiety, and irreversibly binds to an active thiol group of many cysteine proteases, such as papain, actinidase, and cathepsins B, H and L, to form a thioether linkage.

Preparation Note

This E-64 Ready Made Solution is supplied as a proprietary 2.8 mM non-freezing solution formulation.

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N9150SML1283SAE0107
description

Non-freezing solution, 1 mg/mL

description

suitable for cell culture

description

50 mg/mL in DMSO/H2O, 1:1

description

≥98% (HPLC), 7.5mg/ml (50mM) in MES buffer, Autophagy inhibitor

form

ready-to-use solution

form

solution

form

liquid (1:1 DMSO:H2O)

form

liquid

Quality Level

200

Quality Level

-

Quality Level

200

Quality Level

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

wet ice

shipped in

dry ice

shipped in

dry ice

shipped in

ambient


Storage Class

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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