SAB4503582

Anti-KCNAB3 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): K(+) channel subunit β-3, KCNA3B, KCNAB3, Kv-β-3, Voltage-gated potassium channel subunit β-3
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 43 kDa
• species reactivity: human, mouse, rat
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:10000; immunohistochemistry: 1:50-1:100
• NCBI accession no.: O43448
• UniProt accession no.: O43448
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... KCNAB3(9196)

Description

General description

The gene coding for potassium voltage-gated channel subfamily A regulatory β subunit 3 (KCNAB3) is mapped to human chromosome 17p13.1. Human Kvβ3 transcript is mainly expressed in the brain, with high expression levels in cerebellum.

Immunogen

The antiserum was produced against synthesized peptide derived from human KCNAB3.

Immunogen Range: 293-342

Biochem/physiol Actions

Potassium voltage-gated channel subfamily A regulatory β subunit 3 (KCNAB3) is involved in migraine pathogenesis.2 Kvβ3 expressed along with Kv1.5 in Chinese hamster ovary cells gives rise to a new A-type potassium channel.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable