S6377

Sulfisoxazole

≥99.0%

• Synonym(s): 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide, N¹-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide, Sulfafurazole
• Empirical Formula (Hill Notation): C₁₁H₁₃N₃O₃S
• CAS Number: 127-69-5
• Molecular Weight: 267.30
• EC Number: 204-858-9
• UNSPSC Code: 12352200
• PubChem Substance ID: 24899697
• Beilstein/REAXYS Number: 6737262
• MDL number: MFCD00003150

Properties

• assay: ≥99.0%
• solubility: acetone: complete 50 mg/ml, 10% HCl: complete 33 mg/mL, clear, colorless to faintly yellow, alcohol: slightly soluble, chloroform: insoluble
• originator: Roche
• storage temp.: 2-8°C
• SMILES string: Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C
• InChI: 1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3
• InChI key: NHUHCSRWZMLRLA-UHFFFAOYSA-N
• Gene Information: rat ... Ednra(24326)

Description

Application

Sulfisoxazole was one of the antibiotics tested on bacterial reporter panel that gave information on pollution load on the environment.¹¹

Biochem/physiol Actions

Sulfisoxazole, a sulfonamide, is an antibacterial agent that acts by inhibiting the folic acid metabolism.¹ It is also a non-selective endothelin antagonist. It is effective in the treatment of recurrent acute otitis media and also in rendering protection to retina against ischemic-like insults.^2,3

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves