S4562
β-Secretase inhibitor
≥97% (HPLC), powder
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Please contact Customer Service for Availability | 15 300,00 CZK |
About This Item
biological source
synthetic (organic)
Quality Segment
assay
≥97% (HPLC)
form
powder
mol wt
~_1.65 kDa
color
white
mp
200 °C
solubility
DMSO: soluble
shipped in
dry ice
storage temp.
−20°C
SMILES string
N([C@H]([C@@H](O)CC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O)CC(C)C)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CCCCN)[C@H](O)C)CCC(=O)O)C
InChI
1S/C73H118N16O27/c1-11-37(8)59(88-66(108)45(23-27-56(101)102)79-63(105)43(21-25-54(97)98)81-72(114)60(39(10)91)89-62(104)41(75)19-15-16-28-74)71(113)85-49(33-90)68(110)80-44(22-26-55(99)100)65(107)87-58(36(6)7)70(112)83-47(31-51(76)93)67(109)82-46(29-34(2
InChI key
CQTBDEGWLSDJEP-JMAXQNTPSA-N
General description
Application
1 of 1
This Item | |||
|---|---|---|---|
| description ≥97% (HPLC), powder | description recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), ≥10,000 units/mg protein | description The β-Secretase Inhibitor III controls the biological activity of β-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications. | description β-Secretase Inhibitor IV, CAS 797035-11-1, is a cell-permeable inhibitor that binds to BACE-1 active site and blocks its proteolytic activity (IC50 = 15 nM for human BACE-1). |
| form powder | form buffered aqueous solution | form lyophilized | form solid |
| assay ≥97% (HPLC) | assay ≥90% (SDS-PAGE) | assay ≥95% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C |
| solubility DMSO: soluble | solubility - | solubility DMSO: 1 mg/mL | solubility DMSO: 100 mg/mL |
| shipped in dry ice | shipped in wet ice | shipped in ambient | shipped in ambient |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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