S3072
Spiramycin adipate
Synonym(s):
Spiramycin hexanedioate
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form
powder
potency
3948 I.U. per mg
storage condition
(Keep container tightly closed in a dry and well-ventilated place.)
color
off-white
antibiotic activity spectrum
Gram-positive bacteria
Mode of action
protein synthesis | interferes
storage temp.
2-8°C
General description
Chemical structure: macrolide
Application
Biochem/physiol Actions
Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
This product is a mixture of spiramycins I, II, and III.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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O Rolin et al.
Pathologie-biologie, 34(5), 476-478 (1986-05-01)
Experimental septicemia was induced in mice by intraperitoneal injection of 10 to 100 lethal doses of Staphylococcus aureus and Streptococcus pneumoniae. Animals were treated by a mixture of adipic acid and spiramycin (subcutaneous route) or by spiramycin base (oral route)
Acute bronchopulmonary infections: treatment with i.v. spiramycin.
F Vachon and S Kernbaum
Chemotherapia, 6, 282-285 (1987)
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