RAB0734

Human SHBG / Sex Hormone-binding Globulin ELISA Kit

• NACRES: NA.32
• UNSPSC Code: 41116158
• Gene information: human ... SHBG(6462)
• Input: sample type cell culture supernatant(s); sample type plasma; sample type serum
• Species reactivity: human
• Storage temp.: −20°C
• Shipped in: wet ice

Properties

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type cell culture supernatant(s); sample type plasma; sample type serum
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 1.2 pmol/L; standard curve range: 1.229-300 pmol/L
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... SHBG(6462)

Description

General description

Serum sex hormone-binding globulin (SHBG) protein is a homodimer with a signal peptide and two laminin G-like domains. SHBG is produced by testis germ cells and released into the bloodstream by the liver. SHBG gene is located on human chromosome 17p13.1.

Application

Human SHBG/Sex Hormone-binding Globulin ELISA Kit has been used to measure serum sex hormone-binding globulin (SHBG) in whole blood samples.[1] It has also been used to quantify SHBG in maternal peripheral and umbilical cord blood.[2]

Biochem/physiol Actions

Serum sex hormone-binding globulin (SHBG) can bind and transport sex steroids and aid in modulating their biological active fraction. Direct action of SHBG modulates sex steroid actions in target cells. A low level of SHBG is detected in women with polycystic ovary syndrome (PCOS). The SHBG ELISA kit can be used for the quantitative measurement of sex hormone-binding globulin in cell culture supernatants, plasma and serum.

Kit Components Also Available Separately

• RABTMB3

  ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)

  SDS
• RABSTOP3

  ELISA Stop Solution (Item I)

  SDS
• RABWASH4

  20X Wash Buffer (Item B)

  SDS

Safety Information

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• Storage Class: 10 - Combustible liquids