PLA0207

Rabbit anti-ESCO2 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): 2410004I17Rik, ECO1 homolog 2, EFO2, Establishment of cohesion 1 homolog 2, RBS, Roberts syndrome, establishment of cohesion 1 homolog 2 (S. cerevisiae)
• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IP, WB
• Citations: -

Properties

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human
• technique(s): immunoprecipitation (IP): 2-10 μg/mg, western blot: 1:2,000- 1:10,000
• accession no.: NP_001017420.1
• UniProt accession no.: Q56NI9
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: rabbit ... ESCO2(157570)

Description

Immunogen

The epitope recognized by PLA0207 maps to a region between residue 200 and 250 of human establishment of cohesion 1 homolog 2 using the numbering given in entry NP_001017420.1 (GeneID 157570).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

ESCO2 (establishment of cohesion 1 homolog2) is an acetyltransferase that is essential to sister chromatid cohesion during S phase. Recent studies reveal that ESCO2 associates with components of the CoREST transcriptional repression complex. ESCO2 has also been shown to possess histone H3 K9 methylation activity. These findings suggest a role for ESCO2 in transcriptional regulation via the modulation of chromatin structure.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable