PLA0156

Rabbit anti-PPP5C Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): PP-T, PP5, PPP5, PPT, catalytic subunit, protein phosphatase 5, protein phosphatase T
• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IHC, IP, WB
• Citations: -

Properties

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: mouse, human
• technique(s): immunohistochemistry: 1:200-1:1,000, immunoprecipitation (IP): 2-5 μg/mg, western blot: 1:2,000- 1:10,000
• accession no.: NP_006238.1
• UniProt accession no.: P53041
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: rabbit ... PPP5C(5536)

Description

Immunogen

The epitope recognized by PLA0156 maps to a region between residue 1 and 50 of human Protein Phosphatase 5, Catalytic Subunit using the numbering given in entry NP_006238.1 (GeneID 5536).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

PPP5C is the protein phosphatase 5 catalytic unit that is a member of the large PPP family of serine/threonine protein phosphatases. PPP5C plays a role in mediating stress-activated signaling pathways and the DNA damage response. Unlike PP1, PP2A, and PPP4, which function as dimeric or trimeric enzymes, PPP5 functions as a monomer. PPP5 exists as a regulatory N-terminal tetratricopeptide repeat (TPR) domain fused to a C-terminal phosphatase catalytic domain. PPP5C has been demonstrated to associate with and regulate ATM and DNA-PK.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable