PLA0031

Rabbit anti-TRX2 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• UNSPSC Code: 12352203

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• grade: Powered by Bethyl Laboratories, Inc.
• species reactivity: human, gorilla, rhesus monkey, primate, gibbon, chimpanzee
• concentration: 1 mg/mL
• technique(s): ChIP: 1- 5 μg; immunoprecipitation (IP): 5- 10 μg/mg; western blot: 1:500- 1:5,000
• accession no.: NP_055542.1
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: rabbit ... TRX2(9757)

Description

Immunogen

The epitope recognized by PLA0031 maps to a region between residue 2375 and 2425 of human Trithorax 2 using the numbering given in entry NP_055542.1 (GeneID 9757).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Other Notes

Human trithorax homolog 2 (TRX2) is a member of the MLL sub-family of proteins that are found in Set1-like histone H3 K4 methyltransferase complexes. TRX2 may function as a transactivator that mediates cell adhesion and cytoskeletal events important to cell growth and survival. TRX2 is also known as MLL2. The MLL2 complex includes MLL2 (TRX2), ASH2, RBQ3, WDR5, hDPY-30, and menin. MLL2 has been shown to interact with ER-alpha to regulate estrogen-induced gene expression and has been implicated in tumorigenesis.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable