This product has a phosphate group at the 5' end. No information is available regarding the ability of this product to be sensed by cellular RNA sensors.
P4903
poly(C)
Synonym(s):
Polycytidylic acid potassium salt, Poly(C) potassium salt
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| Size/SKU | Availability | Price |
|---|---|---|
10 mg | Please contact Customer Service for Availability | 2 540,00 CZK 2 082,80 CZK |
25 mg | Please contact Customer Service for Availability | 5 060,00 CZK 4 149,20 CZK |
100 mg | Please contact Customer Service for Availability | 17 000,00 CZK 13 940,00 CZK |
About This Item
Form:
powder
Storage temp.:
−20°C
2 082,80 CZK
List Price2 540,00 CZKSave 18%Please contact Customer Service for Availability
Preparation Note
Prepared from CDP using polynucleotide phosphorylase
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This Item | |||
|---|---|---|---|
| description - | description γ-irradiated, 10% Poly (I:C) with buffer salts, TLR ligand tested | description 10% Poly (I:C) with buffer salts, TLR ligand tested | description lyophilized powder |
| Quality Level 200 | Quality Level 200 | Quality Level 300 | Quality Level 200 |
| form powder | form - | form lyophilized powder | form lyophilized powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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What structure is on the 5' end of this RNA (5' monophosphate?) and is this known to be sensed by any cellular RNA sensors?
1 answer-
Helpful?
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What would be the ideal buffer to dissolve the poly(C) in for ideal long-term storage?
1 answer-
The solubility of this product is tested in water at approximately 20 mg/mL. The solubility has not been tested in a buffer solution. However, the Polyuridylic acid potassium salt, P9528, offers a datasheet that notes the material may not be completely soluble in Tris buffer at 1 mg/mL.
Helpful?
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What is the size range? How many nucleotides per molecule?
1 answer-
Unfortunately, the particle size range and nucleotides number are not tested as per the COA of P4903: https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/P4903-100MG0000303636.pdf
There is a reference value for degree of polymerization (DP) available to roughly estimate the nucleotides number, which is ~485. The value could vary lot by lot.Helpful?
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