Archives of otolaryngology--head & neck surgery, 128(4), 365-367 (2002-04-03)
To assess the efficacy of corticosteroid therapy for sudden-onset sensorineural hearing loss at lower frequencies. Retrospective, nonrandomized, controlled study. The recovery rate, recovery/improvement rate, and period between the start of therapy and improvement of symptoms were studied in 2 groups:
Previously we showed that glycation-induced inactivation and loss of antigenicity of enzymes occur simultaneously. Alpha-crystallin, a major structural protein of the mammalian lens, prevents the aggregation of other proteins and protects enzyme function against post-translational modification in vitro. However, it
Glucocorticoid-induced osteoporosis is the most frequently occurring type of secondary osteoporosis. Antagonists of β-adrenergic receptors are now considered to be potential drugs under investigation for osteoporosis. The aim of the present study was to investigate the effects of propranolol, a
To analyse the effects of short-term treatment with etidronate on the glucocorticoid-induced retardation of bone growth and deterioration of bone structure in the prepubertal rat mandible. Fifty 5-week-old male rats were divided into five groups. Etidronate or vehicle treatment (5
Osteonecrosis (ON) of the femoral head is a devastating complication occurring in patients receiving corticosteroid treatment. This study examined the effect of three corticosteroids on the development of ON in rabbits. Thirty-nine rabbits were injected once intramuscularly with either 25
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