P350-05

Porcine Coronary Artery Smooth Muscle Cells: PCASMC (Cryovial)

• NACRES: NA.81
• UNSPSC Code: 41106514
• Biological source: Porcine coronary artery
• Growth mode: Adherent
• Morphology: smooth muscle
• Relevant disease(s): diabetes; stroke; cardiovascular diseases

Properties

• biological source: Porcine coronary artery
• form: solid
• packaging: pkg of 500,000 cells
• manufacturer/tradename: Cell Applications, Inc
• growth mode: Adherent
• karyotype: 2n = 38
• morphology: smooth muscle
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): diabetes; stroke; cardiovascular diseases
• shipped in: dry ice
• storage temp.: −196°C

Description

General description

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PCASMC were used to investigate the role of c-Jun in smooth muscle proliferation, and to show that c-Jun inhibition abrogates smooth muscle cell growth and intimal thickening after arterial injury (Khachigian, 2002). PCASMC were also used to develop poly (l-lactide-co-caprolactone) nanofibrous scaffold material with potential for tissue engineering (Dong, 2008).

Characterization: positive for smooth muscle cell specific alpha-actin expression.

Application

vascular research, supply of blood to heart muscle

Biochem/physiol Actions

Artery

Preparation Note

• 2nd passage, >500,000 cells in Porcine Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO
• Can be cultured at least 16 doublings

Please refer to the PCASMC Culture Protocol.

Other Notes

Porcine Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO

Safety Information

• Storage Class: 11 - Combustible Solids
• flash_point_f: No data available
• flash_point_c: No data available
• wgk: WGK 1