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P0022

PS48

≥98% (HPLC)

Synonym(s):

5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
3 340,00 CZK
25 mg
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13 500,00 CZK

About This Item

Empirical Formula (Hill Notation):
C17H15ClO2
CAS Number:
Molecular Weight:
286.75
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
protect from light

3 340,00 CZK


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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

white to off-white

solubility

DMSO: >20 mg/mL

storage temp.

2-8°C

SMILES string

OC(=O)\C=C(\CCc1ccc(Cl)cc1)c2ccccc2

InChI

1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-

InChI key

LLJYFDRQFPQGNY-QINSGFPZSA-N

Biochem/physiol Actions

PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site.
PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.

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This Item
H6278H7904SML2533
description

≥98% (HPLC)

description

≥70% Z isomer (remainder primarily E-isomer)

description

≥98% Z isomer

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

300

Quality Level

300

Quality Level

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

protect from light

storage condition

protect from light, desiccated

storage condition

protect from light, desiccated

storage condition

-

solubility

DMSO: >20 mg/mL

solubility

ethanol: 20 mg/mL (with heating), methanol: 10 mg/mL

solubility

ethanol: 20 mg/mL (with heating), methanol: 10 mg/mL

solubility

DMSO: 2 mg/mL, clear


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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