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MSST0040

SILu™Lite IFNG Interferon Gamma human

recombinant, expressed in HEK 293 cells, MS Protein Standard

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Synonym(s):

IFNγ, IFN-gamma, Immune interferon, Immuneinterferon

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Size/SKUAvailabilityPrice
50 μg
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17 900,00 CZK

About This Item

NACRES:
NA.12
UNSPSC Code:
23201100
Form:
lyophilized powder
Assay:
≥98% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in HEK 293 cells
Mol wt:
calculated mol wt 17 kDa

17 900,00 CZK

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biological source

human

Quality Segment

recombinant

expressed in HEK 293 cells

assay

≥98% (SDS-PAGE)

form

lyophilized powder

potency

≥98% Heavy amino acids incorporation efficiency by MS

mol wt

calculated mol wt 17 kDa

technique(s)

mass spectrometry (MS): suitable, protein mass spectrometry: suitable

suitability

suitable for mass spectrometry (internal calibrator)

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... IFNG(3458)

General description

Interferon gamma (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. IFNγ is secreted by T helper cells (specifically, Th1 cells), cytotoxic T cells (TC cells) and Natural killer (NK) cells. When combined with other inflammatory cytokines, evaluating the levels of IFNγ can be used as a diagnostic tool in patients with breast cancer or benign prostatic hyperplasia. A recent study evaluated the effect of a cancer vaccine given to patients with colorectal cancer, on the levels of plasma pro-inflammatory cytokines (including IFN-γ). The study concluded that patients achieving stable disease showed increasing levels of plasma inflammatory cytokines.

Immunogen

QDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRG

Biochem/physiol Actions

SILu™Lite IFNG is a recombinant human protein expressed in human 293 cells. It is a homodimer consisting of 138 amino acids Expressed in human 293 cells, with a calculated molecular mass of 17 kDa. SILu Lite IFNG is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.

Physical form

Lyophilized from a solution of phosphate buffered saline.

Legal Information

SILu is a trademark of Sigma-Aldrich Co. LLC

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SILu™Lite IFNG Interferon Gamma human recombinant, expressed in HEK 293 cells, MS Protein Standard

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MSST0040

SILu™Lite IFNG Interferon Gamma human

IFN-γ human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), suitable for cell culture

Sigma-Aldrich

SRP3058

IFN-γ human

Interferon-γ human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), lyophilized powder, suitable for cell culture

Sigma-Aldrich

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Interferon-γ human

Interferon-γ human IFN-gamma, recombinant, expressed in HEK 293 cells, suitable for cell culture, endotoxin tested

Sigma-Aldrich

I17001

Interferon-γ human

description

recombinant, expressed in HEK 293 cells, MS Protein Standard

description

Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), suitable for cell culture

description

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), lyophilized powder, suitable for cell culture

description

IFN-gamma, recombinant, expressed in HEK 293 cells, suitable for cell culture, endotoxin tested

biological source

human

biological source

human

biological source

human

biological source

-

recombinant

expressed in HEK 293 cells

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in HEK 293 cells

assay

≥98% (SDS-PAGE)

assay

≥98% (SDS-PAGE)

assay

≥98% (SDS-PAGE)

assay

≥98% (SDS-PAGE)

technique(s)

mass spectrometry (MS): suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

mol wt

calculated mol wt 17 kDa

mol wt

16.9 kDa

mol wt

~17 kDa

mol wt

16 kDa (glycosylated)

form

lyophilized powder

form

lyophilized

form

lyophilized powder

form

lyophilized powder

Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
046M4782V

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