M8377
α-Methyl-DL-tryptophan
≥98% (TLC), suitable for cell culture
Synonym(s):
α-methyl-tryptophan
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Size/SKU | Availability | Price |
|---|---|---|
100 mg | Please contact Customer Service for Availability | CZK 2,070.00 |
250 mg | Please contact Customer Service for Availability | CZK 3,470.00 |
1 g | Please contact Customer Service for Availability | CZK 10,400.00 |
About This Item
Empirical Formula (Hill Notation):
C12H14N2O2
CAS Number:
Molecular Weight:
218.25
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
Product Name
α-Methyl-DL-tryptophan, crystalline
assay
≥98% (TLC)
Quality Segment
form
crystalline
technique(s)
tissue culture: suitable
color
light yellow
storage temp.
2-8°C
SMILES string
CC(N)(Cc1c[nH]c2ccccc12)C(O)=O
InChI
1S/C12H14N2O2/c1-12(13,11(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,14H,6,13H2,1H3,(H,15,16)
InChI key
ZTTWHZHBPDYSQB-UHFFFAOYSA-N
Application
- Nanoengineered sonosensitive platelets for synergistically augmented sonodynamic tumor therapy by glutamine deprivation and cascading thrombosis.: This study explores the use of a-Methyl-DL-tryptophan in enhancing sonodynamic tumor therapy through the deprivation of glutamine and inducing thrombosis, offering a new approach to cancer treatment (Zhou et al., 2023).
- Transporter targeted gatifloxacin prodrugs: synthesis, permeability, and topical ocular delivery.: This article describes the application of a-Methyl-DL-tryptophan in developing transporter-targeted prodrugs, enhancing drug delivery systems, particularly in ocular treatments (Vooturi et al., 2012).
- SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive breast cancer.: The study investigates the role of a-Methyl-DL-tryptophan in targeting SLC6A14 for treating estrogen receptor-positive breast cancer, highlighting its potential as a therapeutic agent (Karunakaran et al., 2011).
Biochem/physiol Actions
α-methyl-DL-tryptophan is a blocker of ATBo, an amino acid transporter whose expression is upregulated in cancer.
1 of 1
This Item | |||
|---|---|---|---|
| form crystalline | form powder | form powder or crystals | form solid |
| assay ≥98% (TLC) | assay ≥98% (TLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) |
| technique(s) tissue culture: suitable | technique(s) - | technique(s) - | technique(s) - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| color light yellow | color - | color slightly off-white to brown | color white to off-white |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.