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Key Documents

M7795

Sigma-Aldrich

rac-2-Methoxy-3-hexadecanamido-1-propylphosphocholine

≥90%

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About This Item

Empirical Formula (Hill Notation):
C25H53N2O6P
CAS Number:
Molecular Weight:
508.67
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:

Assay

≥90%

form

powder

impurities

≤0.5 mol/mol (NH4)2CO3

solubility

chloroform: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCC(=O)NCC(COP([O-])(=O)OCC[N+](C)(C)C)OC

InChI

1S/C25H53N2O6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-25(28)26-22-24(31-5)23-33-34(29,30)32-21-20-27(2,3)4/h24H,6-23H2,1-5H3,(H-,26,28,29,30)

InChI key

GLZQVYDFXUECNY-UHFFFAOYSA-N

Biochem/physiol Actions

Protein kinase C inhibitor.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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M H Marx et al.
Journal of medicinal chemistry, 31(4), 858-863 (1988-04-01)
Previously unreported analogues of the synthetic antitumor phospholipid ET-18-OMe (1-octadecyl-2-methoxy-rac-glycero-3-phosphocholine), in which the 1-ether oxygen has been replaced by an amido group, have been prepared and evaluated for in vitro cytotoxic effects and for inhibition of protein kinase C. The

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