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α,β-Methyleneadenosine 5′-triphosphate lithium salt

Name: &#945;,&#946;-Methyleneadenosine 5&#8242;-triphosphate lithium salt
Brand: SIGMA
Price: 10600 CZK

≥93% (HPLC), P2 purinoceptor agonist, solid

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Synonym(s):

AMP-CPP

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Size/SKU	Availability	Price
5 mg	Please contact Customer Service for Availability	10 600,00 CZK
10 mg	Please contact Customer Service for Availability	19 500,00 CZK
25 mg	Please contact Customer Service for Availability	41 900,00 CZK
100 mg	Please contact Customer Service for Availability	88 100,00 CZK

About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₈N₅O₁₂P₃ · xLi⁺

CAS Number:

104809-20-3

Molecular Weight:

505.21 (free acid basis)

UNSPSC Code:

41106305

eCl@ss:

32160414

PubChem Substance ID:

24277720

NACRES:

NA.77

MDL number:

MFCD00148925

Assay:

≥93% (HPLC)

Form:

solid

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Properties

Product Name

α,β-Methyleneadenosine 5′-triphosphate lithium salt, ≥93% (HPLC), solid

Quality Segment

200

assay

≥93% (HPLC)

form

solid

color

white

solubility

H₂O: 100 mg/mL

storage temp.

−20°C

SMILES string

[Li+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)CP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C11H18N5O12P3.Li/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(27-11)1-26-29(19,20)4-30(21,22)28-31(23,24)25;/h2-3,5,7-8,11,17-18H,1,4H2,(H,19,20)(H,21,22)(H2,12,13,14)(H2,23,24,25);/q;+1/p-1/t5-,7-,8-,11-;/m1./s1

InChI key

NVHVREPTGDOYIC-YCSZXMBFSA-M

Gene Information

human ... P2RX1(5023)

Description

Application

α,β-Methyleneadenosine 5′-triphosphate lithium salt has been used:

as P2-purinoreceptor agonist (P2X), to analyse its effects on membrane conductance in the astrocytes of caudal nucleus
as a P2X receptor agonist, to increase the calcium current in the neurons in satellite cells
to determine the functional sensitivities of purinergic agonists on P2Y receptors in rat and to determine its effect on developing outer sulcus cells

Biochem/physiol Actions

P2 purinoceptor agonist that is more potent than ATP at the P2X subtype.

Features and Benefits

This compound is featured on the P2 Receptors: P2X Ion Channel Family and P2 Receptors: P2Y G-Protein Family pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Physical form

hygroscopic solid

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This Item	M7510	A2647	A9501
Sigma-Aldrich M6517 α,β-Methyleneadenosine 5′-triphosphate lithium salt	Sigma-Aldrich M7510 β,γ-Methyleneadenosine 5′-triphosphate disodium salt	Sigma-Aldrich A2647 Adenosine 5′-(β,γ-imido)triphosphate lithium salt hydrate	Sigma-Aldrich A9501 Adenosine 3′,5′-cyclic monophosphate
description ≥93% (HPLC), solid	description ≥95%, solid	description ≥93% (HPLC), powder	description ≥98.5% (HPLC), powder
form solid	form solid	form powder	form powder
assay ≥93% (HPLC)	assay ≥95%	assay ≥93% (HPLC)	assay ≥98.5% (HPLC)
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
solubility H₂O: 100 mg/mL	solubility H₂O: 10 mg/mL	solubility H₂O: 50 mg/mL	solubility H₂O: 10 mg/mL, clear, colorless (pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20× more soluble.)
color white	color white	color white	color white

Pictograms

GHS07

Signal Word

Warning

Hazard Codes

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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