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M4910

1-Methylhistamine dihydrochloride

≥98% (TLC), powder

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Synonym(s):

1-Methyl-4-(β-aminoethyl)imidazole dihydrochloride

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Size/SKUAvailabilityPrice
25 mg
Please contact Customer Service for Availability
5 860,00 CZK
100 mg
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18 200,00 CZK

About This Item

Empirical Formula (Hill Notation):
C6H11N3 · 2HCl
CAS Number:
6481-48-7
Molecular Weight:
198.09
UNSPSC Code:
12352204
PubChem Substance ID:
24277805
NACRES:
NA.32
MDL number:
MFCD00037000

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Product Name

1-Methylhistamine dihydrochloride, ≥98% (TLC), powder

Quality Segment

assay

≥98% (TLC)

form

powder

solubility

water: 49.00-51.00 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

Cl[H].Cl[H].Cn1cnc(CCN)c1

InChI

1S/C6H11N3.2ClH/c1-9-4-6(2-3-7)8-5-9;;/h4-5H,2-3,7H2,1H3;2*1H

InChI key

AGXVEALMQHTMSW-UHFFFAOYSA-N

Gene Information

Application

1-Methylhistamine dihydrochloride has been used as a standard in the evaluation of histamine levels in aqueous humor of glaucoma patients by liquid chromatography. It has also been used as a substrate to determine amine oxidase activity.

Biochem/physiol Actions

1-Methylhistamine is present in the brain and is a metabolite of histamine that is metabolized by histamine N-methyltransferase. It acts as a biomarker for histaminergic system activity in the cerebrospinal fluid of patients suffering from Alzheimer′s disease (AD), hypersomnia, and other neurological conditions.
Major metabolite of histamine by histamine N-methyltransferase.

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1 of 1

This Item
M7780H7125H7250
1-Methylhistamine dihydrochloride ≥98% (TLC), powder

Sigma-Aldrich

M4910

1-Methylhistamine dihydrochloride

3-Methylhistamine dihydrochloride analytical standard

Supelco

M7780

3-Methylhistamine dihydrochloride

Histamine ≥97.0%

Sigma-Aldrich

H7125

Histamine

Histamine dihydrochloride ≥99% (TLC), powder

Sigma-Aldrich

H7250

Histamine dihydrochloride

description

≥98% (TLC), powder

description

analytical standard

description

≥97.0%

description

≥99% (TLC), powder

assay

≥98% (TLC)

assay

-

assay

≥97.0%

assay

≥99% (TLC)

solubility

water: 49.00-51.00 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

-

solubility

-

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

form

powder

form

-

form

-

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

Gene Information

human ... HRH1(3269), HRH2(3274), HRH3(11255), HRH4(59340)

Gene Information

-

Gene Information

human ... CA1(759), CA2(760), HRH1(3269), HRH2(3274), HRH3(11255), HRH4(59340)
rat ... Hrh1(24448), Hrh3(85268)

Gene Information

human ... HRH1(3269), HRH2(3274)

Storage Class

11 - Combustible Solids

WGK

WGK 3

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000540791
    0000517051
    0000102189
    0000081238
    0000096928

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