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M3778

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride

≥97% (GC), MAO-A inhibitor, powder

Synonym(s):

Clorgyline

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50 mg
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CZK 3,010.00
100 mg
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CZK 5,030.00
500 mg
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CZK 17,300.00

About This Item

Empirical Formula (Hill Notation):
C13H15Cl2NO · HCl
CAS Number:
17780-75-5
Molecular Weight:
308.63
NACRES:
NA.77
PubChem Substance ID:
24278179
UNSPSC Code:
12352116
EC Number:
241-760-5
MDL number:
MFCD00052012
Assay:
≥97% (GC)
Form:
powder

CZK 3,010.00

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Product Name

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride, ≥97% (GC)

Quality Segment

100

assay

≥97% (GC)

form

powder

solubility

DMSO: 10 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

Cl.CN(CCCOc1ccc(Cl)cc1Cl)CC#C

InChI

1S/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H

InChI key

BBAZDLONIUABKI-UHFFFAOYSA-N

Gene Information

human ... MAOA(4128)
rat ... Maoa(29253), Maob(25750)

Application

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride has been used as a monoamine oxidase A (MAO-A) inhibitor:
  • in MAO-A biochemical assay[1]
  • to study its effects on the transit of serotonin (5-HT) in the human placenta explants[2]
  • to study its effects on human prostate cancer cells[3]

Biochem/physiol Actions

MAO-A inhibitor.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
P8511A3085T3146
N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride ≥97% (GC)

Sigma-Aldrich

M3778

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride

trans-2-Phenylcyclopropylamine hydrochloride

Sigma-Aldrich

P8511

trans-2-Phenylcyclopropylamine hydrochloride

5-(N-Ethyl-N-isopropyl)amiloride

Sigma-Aldrich

A3085

5-(N-Ethyl-N-isopropyl)amiloride

Trimipramine maleate salt ≥98% (TLC), powder

Sigma-Aldrich

T3146

Trimipramine maleate salt

form

powder

form

powder

form

powder

form

powder

assay

≥97% (GC)

assay

≥97% (TLC)

assay

≥98% (TLC)

assay

≥98% (TLC)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 10 mg/mL, clear, colorless to faintly yellow

solubility

ethanol: 50 mg/mL, clear to slightly hazy

solubility

methanol: 9.80-10.20 mg/mL, clear, light yellow to yellow

solubility

chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow

Gene Information

human ... MAOA(4128)
rat ... Maoa(29253), Maob(25750)

Gene Information

human ... MAOA(4128), MAOB(4129)

Gene Information

human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340), SLC9A1(6548), SLC9A5(6553)
mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278)
rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768), Slc9a1(24782), Slc9a2(24783), Slc9a3(24784), Slc9a4(24785)

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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