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M216

MDL 105,519

≥98% (HPLC), NMDA receptor antagonist, solid

Synonym(s):

(E)-4,6-Dichloro-3-(2-phenyl-2-carboxyethenyl)indole-2-carboxylic acid

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Pack SizeSKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
CZK 16,400.00
25 mg
Please contact Customer Service for Availability
CZK 64,900.00

About This Item

Empirical Formula (Hill Notation):
C18H11Cl2NO4
CAS Number:
Molecular Weight:
376.19
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.32
MDL number:

CZK 16,400.00


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Product Name

MDL 105,519, ≥98% (HPLC), solid

Quality Segment

assay

≥98% (HPLC)

form

solid

color

white to off-white

solubility

DMSO: >20 mg/mL

SMILES string

OC(=O)C(=C/c1c([nH]c2cc(Cl)cc(Cl)c12)C(O)=O)\c3ccccc3

InChI

1S/C18H11Cl2NO4/c19-10-6-13(20)15-12(16(18(24)25)21-14(15)7-10)8-11(17(22)23)9-4-2-1-3-5-9/h1-8,21H,(H,22,23)(H,24,25)/b11-8-

InChI key

LPWVUDLZUVBQGP-FLIBITNWSA-N

Gene Information

human ... GRIN1(2902)
rat ... Grin1(24408)

Biochem/physiol Actions

MDL 105,519 is a high affinity N-methyl-D-aspartate (NMDA) glutamate receptor antagonist at the glycine site. It inhibits NMDA-dependent responses.

Legal Information

Sold under exclusive license from Hoechst Marion Roussel, Inc.

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This Item
C104C0496SML0616
assay

≥98% (HPLC)

assay

-

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

solid

form

solid

form

powder

form

powder

Gene Information

human ... GRIN1(2902)
rat ... Grin1(24408)

Gene Information

human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)
rat ... Grin2a(24409)

Gene Information

-

Gene Information

-

color

white to off-white

color

white

color

-

color

white to beige

solubility

DMSO: >20 mg/mL

solubility

H2O: 99.2 mg/mL, ethanol: insoluble

solubility

DMSO: >20 mg/mL

solubility

DMSO: 15 mg/mL, clear


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Global Trade Item Number

SKUGTIN
M216-25MG04061833007662
M216-5MG04061833007679

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