L9536

Anti-Leptin Receptor antibody produced in goat

affinity isolated antibody, lyophilized powder

• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD02096819
• Conjugate: unconjugated
• Clone: polyclonal
• Application: FACS, IHC (f), WB
• Citations: 6

Properties

• biological source: goat
• Quality Segment: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: mouse
• technique(s): flow cytometry: suitable, immunohistochemistry (frozen sections): suitable, western blot: suitable
• UniProt accession no.: P48356
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: mouse ... Lepr(16847)

Description

Immunogen

recombinant mouse leptin receptor expressed in NS0 cells.

Biochem/physiol Actions

Leptin is a hormone secreted by adipocytes and regulates energy homeostasis, inflammation and neuroendocrine processes, synaptic formation and memory condensation. The physiological effects of leptin are mediated by leptin receptors, ObR and LepR. Leptin is the key regulator of obesity and acts directly on neuronal networks to regulate feeding, metabolism, gastric mobility and energy homeostasis. The pathways that mediate the effect of leptin are JAK/STAT, PI3K and JNK.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)