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L4420

LY-367385 hydrochloride

≥98% (HPLC)

Synonym(s):

(S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid

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Size/SKUAvailabilityPrice
5 mg
Please contact Customer Service for Availability
CZK 2,150.00
25 mg
Please contact Customer Service for Availability
CZK 8,140.00
CZK 6,919.00

About This Item

Empirical Formula (Hill Notation):
C10H11NO4 ·HCl
CAS Number:
Molecular Weight:
245.66
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

CZK 2,150.00


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assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

solubility

H2O: >10 mg/mL

originator

Eli Lilly

storage temp.

room temp

SMILES string

Cc1cc(ccc1[C@H](N)C(O)=O)C(O)=O

InChI

1S/C10H11NO4/c1-5-4-6(9(12)13)2-3-7(5)8(11)10(14)15/h2-4,8H,11H2,1H3,(H,12,13)(H,14,15)/t8-/m0/s1

InChI key

SGIKDIUCJAUSRD-QMMMGPOBSA-N

Application

LY-367385 hydrochloride has been used as a non-N-methyl-D-aspartate (NMDA) glutamate receptor blocker in neuronal stimulation experiment.

Biochem/physiol Actions

LY-367385 is a selective metabotropic glutamate 1a receptor (mGlu1a) antagonist.
LY-367385 hydrochloride has an ability to inhibit induction of long-term potentiation (LTP).

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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This Item
H4166R7532SML0234
form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

solubility

H2O: >10 mg/mL

solubility

DMSO: >10 mg/mL

solubility

DMSO: >10 mg/mL, H2O: >2 mg/mL

solubility

DMSO: ≥10 mg/mL at warmed to 60 °C

storage condition

desiccated

storage condition

desiccated

storage condition

desiccated

storage condition

desiccated


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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