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JWH-015

Name: JWH-015
Brand: SIGMA

≥98% (HPLC), powder

Synonym(s):

(2-Methyl-1-propyl-1H-indol-3-yl)-1-naphthalenylmethanone

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About This Item

Empirical Formula (Hill Notation):

C₂₃H₂₁NO

CAS Number:

155471-08-2

Molecular Weight:

327.42

NACRES:

NA.77

PubChem Substance ID:

24278502

UNSPSC Code:

12352200

MDL number:

MFCD02094630

Assay:

≥98% (HPLC)

Form:

powder

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Properties

assay

≥98% (HPLC)

form

powder

drug control

kontrollierte Droge in Deutschland, regulated under CDSA - not available from Sigma-Aldrich Canada

color

off-white

solubility

DMSO: >20 mg/mL (with heating)

storage temp.

−20°C

SMILES string

CCCn1c(C)c(C(=O)c2cccc3ccccc23)c4ccccc14

InChI

1S/C23H21NO/c1-3-15-24-16(2)22(20-12-6-7-14-21(20)24)23(25)19-13-8-10-17-9-4-5-11-18(17)19/h4-14H,3,15H2,1-2H3

InChI key

LJSBBBWQTLXQEN-UHFFFAOYSA-N

Gene Information

human ... CNR2(1269)
rat ... Cnr1(25248)

Description

Application

JWH-015 has been used to study its effect on tumor-evoked pain behavior. It has also been used to study its protective effects on rat brain mitochondria upon paraquat exposure.

Biochem/physiol Actions

JWH-015 is a selective CB2 cannabinoid receptor agonist. JWH-015 is structurally classified as naphthoylindoles.

Features and Benefits

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

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Show Differences

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This Item	G1918	SML0204	SML1932
Sigma-Aldrich J4252 JWH-015	Sigma-Aldrich G1918 Gö 6983	Sigma-Aldrich SML0204 MS-1020	Sigma-Aldrich SML1932 A-1210477
assay ≥98% (HPLC)	assay ≥97%	assay ≥98% (HPLC)	assay ≥98% (HPLC)
form powder	form powder	form powder	form powder
drug control kontrollierte Droge in Deutschland, regulated under CDSA - not available from Sigma-Aldrich Canada	drug control -	drug control -	drug control -
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C
solubility DMSO: >20 mg/mL (with heating)	solubility DMSO: 10 mg/mL, clear	solubility DMSO: ≥10 mg/mL at 60 °C	solubility DMSO: 2 mg/mL, clear

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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