J4144
Jo-1 human
recombinant, expressed in E. coli, solution
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| Size/SKU | Availability | Price |
|---|---|---|
100 μg | Please contact Customer Service for Availability | CZK 10,500.00 |
About This Item
Form:
solution
Recombinant:
expressed in E. coli
Mol wt:
55 kDa by SDS-PAGE
recombinant
expressed in E. coli
Quality Segment
form
solution
mol wt
55 kDa by SDS-PAGE
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... HARS(3035)
General description
Jo-1, or histidyl-transfer ribonucleic acid synthetase, is a homodimeric enzyme that catalyzes the coupling of histidine to its specific transfer RNA (tRNA), prior to transport of histidine to the ribosome, and subsequent incorporation of histidine into polypeptide chains. Jo-1 has been associated with various autoimmune disorders, such as polymyositis and dermatomyositis, and T-cell mediated autoimmunity.
Biochem/physiol Actions
The anti-Jo-1 antibody has been associated with an increased frequency of interstitial pulmonary disease in polymyositis/dermatomyositis patients.
Used in the immunoassay for antibodies to Jo-1.
Physical form
Solution in 6 M urea, 500 mM sodium chloride, 10 mM Tris HCl buffer, pH 8.0.
1 of 1
This Item | |||
|---|---|---|---|
| recombinant expressed in E. coli | recombinant expressed in CHO cells | recombinant expressed in HEK 293 cells | recombinant expressed in HEK 293 cells |
| mol wt 55 kDa by SDS-PAGE | mol wt monomer 57 kDa by calculation | mol wt ~150 kDa by SDS-PAGE | mol wt ~150 kDa by SDS-PAGE |
| form solution | form lyophilized | form liquid | form lyophilized |
| storage temp. −70°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| shipped in dry ice | shipped in wet ice | shipped in wet ice | shipped in wet ice |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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