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I5659

Idebenone

≥98% (HPLC), powder

Synonym(s):

2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione

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Size/SKUAvailabilityPrice
25 mg
Please contact Customer Service for Availability
4 090,00 CZK
100 mg
Please contact Customer Service for Availability
13 600,00 CZK
11 560,00 CZK

About This Item

Empirical Formula (Hill Notation):
C19H30O5
CAS Number:
58186-27-9
Molecular Weight:
338.44
UNSPSC Code:
12352204
PubChem Substance ID:
329815386
NACRES:
NA.25
MDL number:
MFCD00274552

4 090,00 CZK

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Product Name

Idebenone, ≥98% (HPLC)

Quality Segment

200

assay

≥98% (HPLC)

form

powder

solubility

methanol: 50 mg/mL, clear to slightly hazy

storage temp.

room temp

SMILES string

O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O

InChI

1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3

InChI key

JGPMMRGNQUBGND-UHFFFAOYSA-N

General description

Idebenone is a short-chain benzoquinone drug.

Application

Idebenone has been used:
  • to treat mutant myocilin (mMYOC) cells for drug treatment assay
  • to validate C2C12 secondary cell screening assay
  • to treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPARα, δ and γ LBDs

Biochem/physiol Actions

A short-chain Coenzyme Q analog that enhances superoxide formation, presumably by mediating electron transfer from N2 to oxygen.
Idebenone is used in the treatment of visual impairment in adolescents and adults with Leber′s hereditary optic neuropathy (LHON). It serves as an antioxidant. It helps to guard the heart muscle against oxidative stress.

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This Item
A9657PZ0006K4394
Idebenone ≥98% (HPLC)

Sigma-Aldrich

I5659

Idebenone

DL-Aminoglutethimide

Sigma-Aldrich

A9657

DL-Aminoglutethimide

Exemestane ≥98% (HPLC)

Sigma-Aldrich

PZ0006

Exemestane

PKF118-310 ≥98% (HPLC)

Sigma-Aldrich

K4394

PKF118-310

assay

≥98% (HPLC)

assay

≥98% (TLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

solubility

methanol: 50 mg/mL, clear to slightly hazy

solubility

H2O: slightly soluble 0.2 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.2 mg/mL, 0.1 M HCl: soluble, acetonitrile: soluble, methanol: soluble

solubility

DMSO: ≥20 mg/mL

solubility

H2O: 10 mg/mL, clear

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

form

powder

form

powder or crystals

form

powder

form

powder

storage temp.

room temp

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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