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I2142

KN-62

≥95%, powder

Synonym(s):

(S)-5-Isoquinolinesulfonic acid 4-[2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester, 1-[N,O-bis(5-Isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine

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Size/SKUAvailabilityPrice
0.5 mg
Please contact Customer Service for Availability
3 280,00 CZK
1 mg
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4 880,00 CZK
4 148,00 CZK

About This Item

Empirical Formula (Hill Notation):
C38H35N5O6S2
CAS Number:
Molecular Weight:
721.84
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥95%
Form:
powder

3 280,00 CZK


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biological source

synthetic (organic)

Quality Segment

assay

≥95%

form

powder

color

yellow

mp

130 °C

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.93 mg/mL, methanol: 10 mg/mL, DMSO: 12 mg/mL, chloroform: 20 mg/mL

storage temp.

−20°C

SMILES string

O=S(OC1=CC=C(C[C@@H](C(N2CCN(C3=CC=CC=C3)CC2)=O)N(C)S(C4=CC=CC5=C4C=CN=C5)(=O)=O)C=C1)(C6=CC=CC7=C6C=CN=C7)=O

InChI

1S/C38H35N5O6S2/c1-41(50(45,46)36-11-5-7-29-26-39-19-17-33(29)36)35(38(44)43-23-21-42(22-24-43)31-9-3-2-4-10-31)25-28-13-15-32(16-14-28)49-51(47,48)37-12-6-8-30-27-40-20-18-34(30)37/h2-20,26-27,35H,21-25H2,1H3/t35-/m0/s1

InChI key

RJVLFQBBRSMWHX-DHUJRADRSA-N

Gene Information

human ... P2RX7(5027)

Biochem/physiol Actions

Selectively inhibits rat brain Ca2+/calmodulin-dependent protein kinase II.

Features and Benefits

This compound is featured on the Ca/CaMKs and P2 Receptors: P2X Ion Channel Family pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
K1385422708422712
description

≥95%, powder

description

≥98% (HPLC)

description

A cell-permeable, reversible and competitive inhibitor of rat brain CaM kinase II (Ki = 370 nM).

description

InSolution, ≥95%, A cell-permeable, competitive inhibitor of Ca2+/calmodulin-dependent protein kinase II

form

powder

form

powder

form

solid

form

liquid

assay

≥95%

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

methanol: 10 mg/mL, DMSO: 12 mg/mL, chloroform: 20 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.93 mg/mL

solubility

H2O: soluble, DMSO: 1 mg/mL

solubility

DMSO: 5 mg/mL

solubility

-

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

-

biological source

-


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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