If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
I0908
Insulin human
meets USP testing specifications
Synonym(s):
Human insulin
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
50 mg | Please contact Customer Service for Availability | CZK 5,340.00 |
250 mg | Please contact Customer Service for Availability | CZK 9,200.00 |
About This Item
biological source
human
Quality Segment
recombinant
expressed in Saccharomyces cerevisiae
agency
meets USP testing specifications
form
solid
potency
≥27.5 units/mg (dry)
technique(s)
cell culture | mammalian: suitable
UniProt accession no.
application(s)
pharmaceutical (small molecule)
storage temp.
−20°C
InChI key
PBGKTOXHQIOBKM-FHFVDXKLSA-N
Gene Information
human ... INS(3630)
Biochem/physiol Actions
Other Notes
1 of 1
This Item | |||
|---|---|---|---|
| recombinant expressed in Saccharomyces cerevisiae | recombinant - | recombinant expressed in yeast | recombinant - |
| biological source human | biological source semisynthetic | biological source Saccharomyces cerevisiae | biological source - |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable |
| form solid | form powder | form lyophilized powder | form dry powder |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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Is this product sterile or not ? Can this be filtered using a 0.22uM filter after being added in the media ?
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This product is not sterile. It may be filter sterilized using a low protein binding membrane having a 0.2 μm pore size. Typically, the stock solution is filter sterilized when prepared and added aseptically to the media.
See the link below to review the product datasheet for the bovine insulin products. While not the same biological source, the general information does apply to the human source product.Product Datasheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/132/262/i6634pis.pdfHelpful?
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What is the solublity and solution stability for Product I0908, Insulin?
1 answer-
As Product I0908 - Insulin human meets USP specifications, we only report out the USP testing results. In the USP method, Insulin is dissolved in 0.01N HCl. Insulin is readily soluble (10-20 mg/ml) in weak acids.For Product I2643, recombinant human insulin, we indicate the following storage conditions. A stock solution can be stored frozen at -20°C in single-use aliquots. Freeze-thaw cycles should be avoided. Alternatively, it can be stored for up to 12 months at 2-8°C, if it is sterile filtered through a low protein binding membrane or if it contains a suitable bacteriostat, such as 0.1% thimerosal or sodium azide.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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